C60

Description

The C60 fullerene, thanks to its small size, can easily cross the so-called blood-brain barrier. This property can lead to numerous medical applications, especially in the field of nanomedicines, through the implementation of new active compounds that could be used by the brain.

The molecule can act as a semiconductor, conductor and superconductor under specific conditions. Fullerenes can display the photochromic effect, which is a change in light transmission based on intensity.Ability to form compounds with many different sorts of material including the ability to retain other substances inside the molecule and the ability to absorb free radicals.

Fullerenes are relatively safe and inert, and yet have properties that allow the substance to create active derivatives.

Advantages

  • Solvent-free
  • Environmentally friendly synthesis using renewable energy
    (hydroelectric powered plant in Quebec)

Structure

Fullerene C60

Fullerene Carbon C60

SOL5060

99.99% without solvents

Buckminster Fullerene

Applications

  • Treatment of various neuronal problems.
  • Development of new drugs for the brain, associating its antioxidant and antiaggregant properties.
  • Biomedical applications, like the design of high-performance MRI contrast agents and X-ray imaging contrastagents. [1] [2]
  • Light-activated antimicrobial agents. [3]
  • Used as a carrier for gene and drug delivery systems.
  • They are used for serum protein profiling as MELDI material for biomarker discovery.
  • Potential antiviral activity, which has strong implications on the treatment of HIV-infection.
  • Anti-aging agent in the cosmetic sector.
  • Fullerenes can be made to be absorbed by HeLa cells. Recent experiments using HeLa cells in cancer research involves the development of new photosensitizers with increased ability to be absorbed by cancer cells and still trigger cell death. It is also important that a new photosensitizer does not stay in the body for a long time to prevent unwanted cell damage. [4]
References

IC60BA

Description

Fullerenes have attracted the attention due to their potential as antiviral agents and several studies indicate that fullerene derivatives are possible candidates for the development of novel anti-influenza drugs.

Fullerenes have generated considerable interest for their unique structural and chemical properties.

Advantages

Studied properties of fullerene derivatives:

  • Antiproliferative and antibacterial activity
  • Excellent antioxidant activity
  • Inhibitor of HIV-reverse transcriptase

Structure

IC60BA

SOL5065

>99.5% (A)

Indene C60 Bis Adduct

Applications

  • Why is it important to look for new drugs?.
  • Quick development of drug-resistance.
  • Frequent mutations of strains.
  • To have especially active small molecular inhibitors in controlling pandemics while vaccines are developed.
References